-Genomic Data for OVOL2 Links
Protein
OVOL2
UniPROBE Accession Number
UP00608
Species
Homo sapiens
Domain
zf-C2H2
Swiss-Prot
Q9BRP0
Name and Synonyms
Name: transcription factor Ovo-like 2.
Synonyms:bA504H3.3, EUROIMAGE566589, hOvo2, Transcription factor Ovo-like 2, Zinc finger protein 339, ZNF339
IHOP
101748
NCBI RefSeq
NP_067043
Description
Zinc-finger transcription repressor factor. Plays a critical role to maintain the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition mainly through the up-regulation of ZEB1 expression. Positively regulates neuronal differentiation (By similarity). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1.
JASPAR
None Available
-PBM Motif Data for OVOL2_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
G.ACCGTTA E.S. 0.497
TAACGGT.C E.S. 0.497
Downloads
Download the zip of all OVOL2_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for OVOL2_D228E_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
A.ATAACGG E.S. 0.497
CCGTTAT.T E.S. 0.497
Downloads
Download the zip of all OVOL2_D228E PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for OVOL2 (all alleles)
Downloads
Download the zip of all OVOL2 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-OVOL2 Datasets
Clone Clone Type Last Modified Save View
OVOL2_REF DNA binding domain only search save
OVOL2_REF Insert Sequence
1    KIKFTTGTCS DSVVHSCDLC GKGFRLQRML NRHLKCHNQV KRHLCTFCGK
51   GFNDTFDLKR HVRTHTGIRP YKCNVCNKAF TQRCSLESHL KKIHGVQQQY
101  AYKQRRDKLY VCEDCGYTGP TQEDLYLHVN SAHPGSSFLK KTSKKLAA


OVOL2_D228E DNA binding domain only search save
OVOL2_D228E Insert Sequence
1    KIKFTTGTCS DSVVHSCDLC GKGFRLQRML NRHLKCHNQV KRHLCTFCGK
51   GFNDTFDLKR HVRTHTGIRP YKCNVCNKAF TQRCSLESHL KKIHGVQQQY
101  AYKQRRDKLY VCEDCGYTGP TQEELYLHVN SAHPGSSFLK KTSKKLAA


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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